
Buy DSIP 5mg UK | Research Grade Peptide
Nonapeptide involved in sleep regulation and stress research.
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Product Description
DSIP (Delta Sleep-Inducing Peptide) is a neuropeptide consisting of nine amino acids with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. It was first identified in 1977 from cerebral venous blood of rabbits during induced sleep. Research has examined its role in sleep regulation, stress modulation, and neuroendocrine activity. DSIP has been studied for its effects on circadian rhythm regulation and its interactions with the hypothalamic-pituitary axis, making it a compound of interest in sleep physiology and stress-response research. Supplied at ≥98% HPLC-verified purity with batch documentation.
This product is intended for in-vitro research and laboratory use only. Not for human consumption.
Storage & Handling
Research Overview
DSIP (Delta Sleep-Inducing Peptide) is a neuropeptide consisting of nine amino acids with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. First identified in 1977 from cerebral venous blood of rabbits during electrically induced sleep by Swiss researchers Schoenenberger and Monnier, DSIP has since been studied for its role in sleep architecture regulation, stress response modulation, and neuroendocrine activity. Research has examined DSIP's effects on circadian rhythm regulation, its interactions with the hypothalamic-pituitary axis, and its potential influence on cortisol and ACTH levels during stress responses. Studies have documented effects on delta wave sleep patterns, from which the peptide derives its name. DSIP research extends beyond sleep physiology into areas including opioid receptor modulation, withdrawal symptom attenuation, and free radical scavenging activity. The peptide's stability in serum and its ability to cross the blood-brain barrier make it a practical research tool in sleep physiology and chronobiology. Its effects on reducing corticotropin levels suggest involvement in stress-adaptive pathways, adding complexity to its pharmacological profile beyond simple sleep induction.
Product Specifications
Laboratory Handling
- Store lyophilised vials at -20°C. Reconstituted DSIP should be refrigerated at 2-8°C and used within 4 weeks.
- Reconstitute with bacteriostatic water using gentle swirling. Avoid shaking or vortexing the peptide solution.
- Handle under aseptic laboratory conditions using sterile equipment throughout reconstitution and aliquoting.
- Avoid repeated freeze-thaw cycles. Prepare measured aliquots from reconstituted stock for consistent experimental use.
Frequently Asked Questions
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