TB-500 5mg research peptide lyophilised powder
Peptides

Buy TB-500 5mg UK | Research Grade Peptide

Synthetic fraction of thymosin beta-4 protein. Cell migration research.

Certificate of Analysis

Third-party tested · HPLC-UV/MS verified

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For research use only. Not for human consumption.

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£22.99/ 5mg vial
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Batch Documentation

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Research grade
Batch documentation

Product Description

TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human and animal cells. Research has focused on its role in cell migration, blood vessel growth, and cell differentiation. Studies have examined its potential in tissue repair and regeneration processes. TB-500 contains the active region of thymosin beta-4 responsible for actin-binding and cell motility, making it a widely referenced compound in cell biology and wound healing research. Each vial is verified at ≥98% purity by HPLC analysis with batch documentation included.

This product is intended for in-vitro research and laboratory use only. Not for human consumption.

Storage & Handling

Storage-20°C long term, +4°C short term up to 4 weeks
FormLyophilised powder
ReconstitutionBacteriostatic water recommended
Stability24 months unopened, 4 weeks reconstituted at +4°C

Product Specifications

CAS Number77591-33-4
Molecular Weight6963 g/mol
Purity≥98% by HPLC
FormLyophilised powder

Research Overview

TB-500 is a synthetic version of Thymosin Beta-4 (Tβ4), a 43-amino-acid protein that occurs naturally in blood platelets, wound fluid, and virtually all nucleated mammalian cells. Research on TB-500 concentrates on its roles in actin regulation, cellular migration, and systemic tissue repair processes. The compound is distinguished from BPC-157 by its systemic mechanism of action — while BPC-157 is thought to act locally at injury sites, TB-500 promotes cell migration and differentiation throughout the body by sequestering G-actin monomers and regulating cytoskeletal dynamics. This systemic activity has led to extensive research in wound healing models, cardiac tissue repair following ischaemic events, hair follicle regeneration, and inflammatory response modulation. TB-500 contains the active domain of Thymosin Beta-4 responsible for actin binding and cell motility, making it a critical research tool in cell biology. Studies have examined its ability to promote endothelial cell migration, keratinocyte migration, and collagen deposition in various preclinical wound models. The compound's role in modulating inflammatory cytokines adds a further dimension to its research profile.

Product Specifications

TB-500 — Technical Data
Molecular FormulaC₁₂₉H₂₁₀N₃₆O₃₉
Molecular Weight2888.2 g/mol
Purity99.019% (Janoshik Analytical, HPLC)
BatchBT5
Storage-20°C lyophilised, 2-8°C reconstituted
AppearanceWhite to off-white lyophilised powder
FormLyophilised powder

Laboratory Handling

  • Store lyophilised vials at -20°C. Reconstituted TB-500 should be kept at 2-8°C and used within 4 weeks.
  • Reconstitute with bacteriostatic water using gentle swirling. Do not vortex to preserve peptide integrity.
  • Use aseptic technique during all handling. Sterilise injection surfaces with alcohol swabs before piercing vial stoppers.
  • Aliquot reconstituted solution to avoid repeated freeze-thaw cycles which can reduce peptide activity.

Frequently Asked Questions

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