Growth Hormone Secretagogues
Ipamorelin
10mg
Ghrelin-receptor agonist pentapeptide, 10mg vial.
99.61% purity · Supplier-reported analysis · Batch UKPL-9516 · View certificate
- Same-day dispatch before 3pm, Mon to Fri
- Add £39.01 more for free UK delivery
- Cold-chain shipping. Always. Dry-cold pack, Royal Mail Tracked 24
- Lost, damaged or wrong? Replaced free if you tell us within 48 hours.
- Research use only. For in-vitro laboratory research. Not for use in humans or animals, or in food, drugs or diagnostics. Not evaluated by the MHRA or FDA. The buyer is responsible for handling and regulatory compliance.
Bulk Pricing
Counted across your basket, any mix of products.
| Vials in basket | Discount | Per vial |
|---|---|---|
| 1 | None | £29.99 |
| 3-4 | 5% | £28.49 |
| 5-9 | 8% | £27.59 |
| 10-50 | 12% | £26.39 |
Bacteriostatic Water 10ml
Required to reconstitute lyophilised peptides.
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) with selective agonist activity at the ghrelin receptor. Research has examined its growth hormone secretagogue activity and its selectivity profile relative to other GHRP-class peptides. This 10mg presentation is the higher-mass research format of our 5mg vial.
Full description
Ipamorelin 10mg holds twice the lyophilised mass of our 5mg vial, in the same single-vial glass format. The compound is identical: the pentapeptide Aib-His-D-2-Nal-D-Phe-Lys-NH₂, molecular weight 711.85 g/mol, CAS 170851-70-4. It is a selective agonist at GHS-R1a, the ghrelin receptor. Raun and colleagues (Eur J Endocrinol, 1998) described it as the first selective growth hormone secretagogue. It came from a series of compounds that lack the central Ala-Trp dipeptide of GHRP-1.
Ipamorelin Research Applications
- Potency in vitro: in primary rat pituitary cells ipamorelin released GH with an EC50 of 1.3 nmol/l and an Emax of 85%. GHRP-6 gave 2.2 nmol/l and 100% (Raun et al., 1998).
- Selectivity: in swine it did not raise ACTH or cortisol even at more than 200 times the ED50 for GH release (Raun et al., Eur J Endocrinol, 1998). FSH, LH, PRL and TSH were unaffected.
- Bone growth: Johansen and colleagues (Growth Horm IGF Res, 1999) reported faster longitudinal bone growth in adult female rats, from 42 to as much as 52 µm/day. Total IGF-I did not change.
- Kinetics: Gobburu and colleagues (Pharm Res, 1999) built a pharmacokinetic-pharmacodynamic model of ipamorelin and the GH response.
Study details
Typical designs use ipamorelin as the selective agonist control in GHS-R1a binding or calcium-mobilisation assays in transfected cell lines. Others study pulsatile GH release or bone metabolism, or pair it with a GHRH-receptor agonist such as CJC-1295. The 10mg vial suits concentration-response matrices, long time-course work and analytical method development. Running the whole design on one batch keeps a single purity figure and certificate behind the dataset.
The 10mg Vial vs the 5mg Vial: Content, Cost and Working Life
Both vials hold the same peptide, so the choice is about logistics. At a fixed fill volume the 10mg vial reaches twice the concentration, so scale the water to the concentration your protocol needs. Cost per milligram falls with vial size, because vial, stopper, freeze-drying and testing costs are paid per vial. One batch and one certificate also cover twice as much work. Ipamorelin has no methionine, cysteine or tryptophan, so a longer in-use window carries less oxidation risk than for many peptides. What does grow is the number of stopper punctures and the working life of one stock, which aliquoting at reconstitution handles.
Research Overview
The receptor behind ipamorelin was identified by Howard and colleagues (Science, 1996). Its natural ligand, ghrelin, was found by Kojima and colleagues (Nature, 1999). Its D-amino acids and aminoisobutyric acid residue make it resistant to protease breakdown.
Ten milligrams in the same vial format means twice the concentration at a given fill volume. Record the concentration against the batch number when you reconstitute. A 10mg vial is usually opened over a longer period, so sterile technique and single-use aliquots matter more than on a 5mg vial.
Product Specifications
- Molecular Formula
- C₃₈H₄₉N₉O₅
- Molecular Weight
- 711.85 g/mol
- CAS Number
- 170851-70-4
- Sequence
- Aib-His-D-2-Nal-D-Phe-Lys-NH₂
- Vial Content
- 10mg lyophilised peptide
- Purity
- 99.61% (HPLC, supplier-tested)
- Batch
- UKPL-9516
- Storage
- -20°C lyophilised, 2-8°C reconstituted
- Appearance
- White lyophilised powder
- Form
- Lyophilised powder
Certificate of Analysis
Supplier-reported analysis. Independent third-party verification pending.
- Batch
- UKPL-9516
- Purity
- 99.61%
- Specification
- ≥98.0%
- Method
- RP-HPLC
- Tested
- Sep 2026
Need the certificate for an earlier batch? Request an older CoA
Storage and Reconstitution
Store the sealed powder at -20°C, away from light and moisture. Reconstituted ipamorelin keeps for up to 4 weeks in the fridge at 2-8°C. On a 10mg vial the risks are repeated stopper punctures and freeze-thaw of one long-lived stock, not air exposure. Aliquot at reconstitution, freeze the aliquots, and thaw each one once.
Vials are sold on their own, without bacteriostatic water for mixing or other supplies.
How to reconstitute and handle
Let the vial and the bacteriostatic water reach room temperature, then swab both stoppers with alcohol. Add the water slowly down the inside wall of the vial, not onto the powder, and swirl gently until dissolved. Do not shake or vortex. The solution should be clear and colourless. Label the vial with the reconstitution date and the concentration.
- Scale the fill volume to your target concentration. A volume carried over from 5mg work will give twice the concentration.
- With no methionine, cysteine or tryptophan in the sequence, sterility is the main limiting factor.
- Return aliquots to cold storage promptly and do not work from a stock left out across a session.
For the full method, see the peptide reconstitution guide and the reconstitution calculator.
Research References
- Ipamorelin, the first selective growth hormone secretagogue (Eur J Endocrinol, 1998)
- Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats (Growth Horm IGF Res, 1999)
- Pharmacokinetic-pharmacodynamic modeling of ipamorelin in human volunteers (Pharm Res, 1999)
Published research on Ipamorelin is indexed on PubMed.
Ipamorelin Price (UK)
Ipamorelin is for sale in 2 vial sizes, priced from £21.99 for 5mg to £29.99 for 10mg. Every size ships from our UK facility, each with its own batch certificate. UK delivery is £4.50 by Royal Mail Tracked 24, free over £69.
| Vial | Price | Cost per mg | Availability |
|---|---|---|---|
| Ipamorelin 5mg | £21.99 | £4.40 | In stock |
| Ipamorelin 10mgThis page | £29.99 | £3.00Best value | In stock |
Prices are in GBP per vial and match the basket. See the FAQ for delivery and payment options, and quality & testing for how each batch is checked.
Frequently Asked Questions
What is in an Ipamorelin 10mg vial?
Ten milligrams of ipamorelin as white lyophilised powder, twice the content of the 5mg vial. The sequence is Aib-His-D-2-Nal-D-Phe-Lys-NH₂, molecular weight 711.85 g/mol, CAS 170851-70-4. The supplier's certificate for batch UKPL-9516 reports 99.61% purity by HPLC and a quantity assay confirming the 10mg content.
How does the Ipamorelin 10mg vial differ from the 5mg vial?
Only in the mass of peptide. The compound, sequence and powder are the same. A 10mg vial reaches twice the concentration at a given reconstitution volume, and all of it shares one reconstitution date once opened. One batch and certificate cover twice as much work. Each size has its own batch and certificate.
Does a 10mg vial of ipamorelin need special handling?
Not beyond normal care. Ipamorelin has no methionine, cysteine or tryptophan, the residues that make larger vials of other peptides prone to oxidation. The limits on a 10mg vial are sterility and wear: a longer working life and more stopper punctures on one stock. Split it into single-use aliquots when you reconstitute and hold them at -20°C.
How much bacteriostatic water does an Ipamorelin 10mg vial need?
It depends on the concentration your protocol specifies, so there is no fixed figure, and we give no dosing information. The arithmetic is mass divided by volume. 10mg in 2mL gives a 5mg/mL stock, and 10mg in 1mL gives 10mg/mL. Do not carry volumes over unchanged from the 5mg vial.
Is the 10mg vial the same compound as the 5mg vial?
Yes. Both hold the identical pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH₂, 711.85 g/mol, CAS 170851-70-4. The 10mg vial is not a stronger material; it holds twice as much. Each size has its own batch and certificate, and at the same fill volume the 10mg vial gives twice the concentration.
What purity is your Ipamorelin 10mg and is it supplier-tested?
Yes, it is supplier-tested. Batch UKPL-9516 measured 99.61% by HPLC, and the certificate is published here instead of on request. Independent third-party verification is pending. Check that the batch number on your vial matches the certificate. Purity alone does not tell you how much peptide is in the vial, so the quantity assay matters too.
Where can I buy Ipamorelin 10mg in the UK?
UK Peptide Lab has Ipamorelin 10mg for sale in the UK from local stock, alongside the 5mg vial. Orders placed before 3pm on a working day are dispatched the same day by Royal Mail Tracked, and UK delivery is free over £69. Buyers must be 18 or over and confirm research-only use.
What purity is the Ipamorelin 10mg vial?
99.61% by HPLC for the current batch, UKPL-9516, on the supplier's analysis. The same certificate reports 10.04mg measured content against the 10mg label. Independent third-party verification is pending. The 5mg vial is a separate batch with its own certificate, so this figure applies to the 10mg batch only.
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